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The maximum recommended dosage of Cialis is 20 milligrams (mg) once daily if you take it as needed to treat erectile dysfunction (ED). For all other Cialis-approved uses, the recommended maximum dosage is 5 mg once daily. Learn about Cialis and dosage by viewing this article. Side effects. For details about Cialis s side effects, see this article. You can also look at the Cialis prescribing information. Interactions. Tadalafil has linear pharmacokinetics over the dose range of 2.5 20 mg.12 A steady state of tadalafil is reached after 5 days of daily administration, with a plasma concentration that is roughly 1.6 times higher than that of a single dose.12 In other words, cumulative plasma exposure at steady state of a 5-mg daily dose corresponds roughly to
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